Status:
COMPLETED
Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction by Biomarkers
Lead Sponsor:
Karolinska Institutet
Collaborating Sponsors:
University Hospital, Linkoeping
Conditions:
Acute Myocardial Infarction (AMI)
Acute Coronary Syndrome (ACS)
Eligibility:
All Genders
30+ years
Phase:
PHASE3
Brief Summary
Oxygen treatment is widely used in acutely ill patients, both pre-hospital and in hospital. The indication for oxygen is sometimes unquestionable, such as in many hypoxic patients, but in other situat...
Detailed Description
The DETermination of the role of OXygen i suspected Acute Myocardial Infarction (DETO2X-AMI) trial (NCT01787110), an ongoing multicentre, randomized, registry based clinical trial, is investigating th...
Eligibility Criteria
Inclusion
- symptoms (chest pain, dyspnea) indicating acute myocardial ischemia within the last 6 hours
- ECG changes (ST-segment elevation ≥ 2 mm V1-V4, or ≥ 1 mm in other leads, ST-segment depression \>1 mm in any lead, negative T-wave in leads V2-V6, pathological Q-wave in at least 2 adjacent leads), left bundle branch block
- and/or elevated levels of cardiac troponin levels in the emergency department indicating acute myocardial ischemia
- oxygen saturation ≥90% (pulse oximeter)
- age ≥30
Exclusion
- unwillingness to participate
- inability to comprehend given information
- continuous oxygen delivery at home prior to inclusion
- cardiac arrest prior to inclusion
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2015
Estimated Enrollment :
175 Patients enrolled
Trial Details
Trial ID
NCT02290080
Start Date
October 1 2014
End Date
December 1 2015
Last Update
December 11 2017
Active Locations (2)
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1
Linköping University Hospital
Linköping, Sweden, 58191
2
Södersjukhuset
Stockholm, Sweden, 11883