Status:

COMPLETED

CBT Insomnia Teens: Augmenting SSRIs to Improve Youth Depression

Lead Sponsor:

Kaiser Permanente

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

Insomnia

Depression

Eligibility:

All Genders

12-19 years

Phase:

NA

Brief Summary

This study is a randomized controlled trial that tests the effectiveness of cognitive behavior therapy (CBT) for insomnia with comorbid depression in youth aged 12 through 19 who have recently begun s...

Detailed Description

160 youth with depression and comorbid insomnia who have just initiated a course of SSRI antidepressants will be randomized to insomnia-focused cognitive behavior therapy (CBT-I) or an attention contr...

Eligibility Criteria

Inclusion

  • Age 12 to 19
  • Major depression based on Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria
  • Recent dispense of SSRI antidepressant
  • Subjective complaint of insomnia ≥ one month
  • Score of ≥ 9 on Insomnia Severity Index

Exclusion

  • Active, progressive physical illness or neurological degenerative disease
  • Sleep apnea, restless legs, or limb movements during sleep
  • Diagnosis of delayed sleep phase syndrome (DSPS)
  • Mental retardation, autism spectrum disorder (ASD), or other significant pervasive developmental disability (PDD)
  • Sleep treatments including over-the-counter (OTC) sleep medication or CBT for insomnia
  • Medications known to alter sleep
  • Diagnosis of bipolar disorder, schizophrenia, or other psychotic disorder

Key Trial Info

Start Date :

March 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2018

Estimated Enrollment :

165 Patients enrolled

Trial Details

Trial ID

NCT02290496

Start Date

March 1 2015

End Date

July 1 2018

Last Update

December 17 2018

Active Locations (1)

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Kaiser Permanente Center for Health Research/Northwest

Portland, Oregon, United States, 97227