Status:
UNKNOWN
Effect of High-flow Nasal Oxygen on Extubation Outcome
Lead Sponsor:
Mackay Memorial Hospital
Conditions:
Respiratory Failure
Congestive Heart Failure
Eligibility:
All Genders
18-95 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether high flow nasal cannula is effective in lowering the reintubation rate after extubation for high risk patients in medical intensive care unit
Detailed Description
The study hypothesis is that Optiflow may reduce the extubation failure rate for high risk patients in medical intensive care unit.In the intervention group, patients fulfilling inclusion criteria and...
Eligibility Criteria
Inclusion
- Patients mechanically ventilated for \> 48 hours and at least one of the following:
- \> 65 y/o
- Cardiac failure as the primary indication of mechanical ventilation
- COPD
- Bronchiectasis
- Old pulmonary tuberculosis with destructive lung
- Chronic renal failure
- Neuromuscular disease
- BMI \> 30
- Inability to manage respiratory secretions
- ARDS
Exclusion
- Presence of tracheostomy
- Recent facial trauma
- Active gastro-intestinal bleeding
- Planned NIPPV support after extubation
Key Trial Info
Start Date :
December 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2016
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT02290548
Start Date
December 1 2014
End Date
October 1 2016
Last Update
December 15 2014
Active Locations (1)
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1
Mackay Memorial Hospital
Taipei, Taiwan