Status:
COMPLETED
Blood Flow Regulation in Glaucoma
Lead Sponsor:
Medical University of Vienna
Conditions:
Glaucoma
Eligibility:
All Genders
18+ years
Brief Summary
Glaucoma is one of the leading causes for blindness in industrialized countries. It is characterized by a progressive loss of retinal ganglion cells, morphological changes in the optic nerve head and ...
Eligibility Criteria
Inclusion
- Patients with open angle glaucoma:
- \- Diagnosis of manifest open angle glaucoma as defined as pathological optic disc appearance, glaucoma hemifield test outside normal limits and/or untreated intraocular pressure ≥ 21 mmHg on at least three measurements in the medical history. Mean deviation in the visual field test \< 10 decibel
- Healthy control subjects:
- normal ophthalmic findings and intraocular pressure \< 20 mmHg on at least three measurements
- no evidence of increased intraocular pressure in the medical history
- no signs of glaucomatous damage in the optic disc or the glaucoma hemifield test
Exclusion
- Presence or history of a severe medical condition as judged by the investigator
- Abuse of alcoholic beverages
- Participation in a clinical trial in the 3 weeks preceding the study
- Exfoliation glaucoma
- Pigmentary glaucoma
- Secondary glaucoma
- Ocular hypertension
- History of acute angle closure
- Intraocular surgery within the last 6 months
- History of epilepsia
- Diabetes mellitus
- Ocular inflammation or infection within the last 3 months
- Untreated hypertension with systolic blood pressure \>160 mmHg, diastolic blood pressure \>95 mmHg
- Pregnancy or lactating
Key Trial Info
Start Date :
April 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 28 2016
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT02292381
Start Date
April 1 2014
End Date
November 28 2016
Last Update
September 1 2021
Active Locations (1)
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1
Medical University of Vienna
Vienna, Austria, 1090