Status:

COMPLETED

Genetic and Epigenetic Mechanisms Underlying Cocoa Health Benefits

Lead Sponsor:

Société des Produits Nestlé (SPN)

Conditions:

Healthy

Eligibility:

All Genders

18-40 years

Phase:

NA

Brief Summary

Evaluate if gene expression changes in SOD2 explain the health benefits of high polyphenols cocoa

Detailed Description

Evaluate if gene expression changes in SOD2 explain the health benefits of high polyphenols cocoa.

Eligibility Criteria

Inclusion

  • Healthy adults
  • BMI between 18.5 and 30 kg/m2
  • Sedentary to moderate physical activity habits

Exclusion

  • Consumption of dietary supplements, antioxidants or anti-inflammatory medication, such as aspirin, ibuprofen, naproxen, or any medication that can affect the study outcomes
  • Actively smoking
  • Suspected abuse of alcohol or illicit drugs
  • Significant illness within two weeks prior to study start or any active systemic infection or medical condition that may require treatment or therapeutic intervention during the study
  • Subject who cannot be expected to comply with study procedures
  • Currently participating or having participated in another clinical trial during last 4 weeks prior to the beginning of this study
  • Consumption of chocolate or its derivates 24 hours before the blood sample taken

Key Trial Info

Start Date :

June 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2014

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT02292576

Start Date

June 1 2012

End Date

August 1 2014

Last Update

November 17 2014

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