Status:
COMPLETED
Maternal Microchimerism in Lymph Nodes of Infants With Biliary Atresia at Time of Kasai's Operation
Lead Sponsor:
Medizinische Hochschule Brandenburg Theodor Fontane
Collaborating Sponsors:
Johann Wolfgang Goethe University Hospital
Conditions:
Biliary Atresia
Eligibility:
All Genders
4-5 years
Brief Summary
Maternal microchimerism has been discussed as an etiological mechanism in infantile (perinatal) biliary atresia (BA). In Kasai's operation (resection of the liver hilum plaque followed by hepato-porto...
Detailed Description
Upon operation of infants with non-syndromatic biliary atresia (BA, commonest form), surgeons almost invariably note the prominent finding of multiple swollen lymph nodes of up to 2 cm in size in the ...
Eligibility Criteria
Inclusion
- Non-Syndromatic Form of Biliary Atresia
Exclusion
- Syndromatic Form of Biliary Atresia
- Other Congenital Liver Disease (Like Alagilles' Syndrome)
- No liver fibrosis/cirrhosis in Histology of LIver Specimen from Routine Histology
Key Trial Info
Start Date :
November 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2014
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT02292862
Start Date
November 1 2012
End Date
November 1 2014
Last Update
November 17 2014
Active Locations (1)
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1
Pediatric Surgery Department
Hanover, Lower Saxony, Germany, 30625