Status:
COMPLETED
Methadone in Ambulatory Surgery
Lead Sponsor:
Washington University School of Medicine
Conditions:
Post-operative Pain
Anesthesia
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The μ-opioid receptor agonist methadone is frequently used in adult anesthesia and adult pain therapy. Methadone has an extremely long half-life, which confers therapeutic advantage by providing more ...
Eligibility Criteria
Inclusion
- Age 18-65 years
- Undergoing general anesthesia and moderately painful, ambulatory surgical procedures with anticipated overnight, postop hospital stay of \< 24 hours
- Signed, written, informed consent
Exclusion
- History of or known liver or kidney disease.
- Females who are pregnant or nursing.
- Opioid tolerant patients (e.g. preoperative methadone therapy or use of fentanyl transdermal patches)
- History of allergy to methadone
Key Trial Info
Start Date :
December 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 12 2018
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02300077
Start Date
December 1 2014
End Date
February 12 2018
Last Update
May 17 2019
Active Locations (1)
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1
Barnes-Jewish Hospital
St Louis, Missouri, United States, 63110