Status:

UNKNOWN

Long Term Postoperative Cognitive Dysfunction in the Elderly Patients

Lead Sponsor:

Pusan National University Yangsan Hospital

Conditions:

Cognitive Impairment

Eligibility:

All Genders

60+ years

Phase:

PHASE4

Brief Summary

The purposes of this study are to determine whether long-term postoperative cognitive dysfunction (POCD) is occured after general anesthesia and anesthetic drugs have an effect on the result about POC...

Detailed Description

In present aging society, a surgery in geriatric patient is increasing. Patients older than 60 year are particularly affected for postoperative cognitive dysfunction (POCD) (26-41%). The patients expe...

Eligibility Criteria

Inclusion

  • ≥ 60 years old, scheduled for laparoscopic cholecystectomy under general anesthesia

Exclusion

  • diseases of the central nervous system, including dementia (Mini Mental Examination Score \<24),
  • consumption of major tranquilizers or antidepressants
  • previous neuropsychological testing
  • the patient's inability to comply and follow procedures or poor comprehension of the language used in the study.
  • Parkinson's disease
  • Patients with a severe visual or auditory handicap, illiteracy
  • alcoholism (intake of \>5 units of alcohol daily during the last 3 months)
  • drug dependence
  • those not expected to complete the postoperative tests were excluded as well

Key Trial Info

Start Date :

December 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2016

Estimated Enrollment :

190 Patients enrolled

Trial Details

Trial ID

NCT02301676

Start Date

December 1 2014

End Date

December 1 2016

Last Update

December 2 2014

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