Status:
COMPLETED
Dexamethasone and Wound Healing After Thyroid Surgery
Lead Sponsor:
Quanhong Zhou
Conditions:
Wound Infection
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Dexamethasone is a potent glucocorticoid with analgesic and anti-emetic effects \[1-3\]. Perioperative single-dose dexamethasone therapy has been used for several purposes: to reduce post-operative na...
Detailed Description
Patients who has the thyroid surgery for their thyroid cancer will be randomly allocated into two groups, either dexamethasone group or saline group. In the dexamethasone group, patients will receive ...
Eligibility Criteria
Inclusion
- Elective total thyroidectomy or hemithyroidectomy with lymphadenectomy for thyroid cancer
Exclusion
- Age \> 65 years, \< 18 years
- Thyroid tumor with Grave's disease
- Thyroid tumor size over 5 cm
- Second or more than 2 times for thyroid surgery
- Non-traditional pathway for thyroid surgery
- ASA \> II
- Pharyngitis
- Smoking, alcohol drinking history
- Contraindication or long term use of dexamethasone (allege, ulcer bleeding history, et al)
Key Trial Info
Start Date :
October 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2015
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT02304250
Start Date
October 1 2013
End Date
July 1 2015
Last Update
November 30 2015
Active Locations (1)
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1
Shanghai 6Th People'S Hospital
Shanghai, Shanghai Municipality, China, 200233