Status:

COMPLETED

Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis Compared to Mammography

Lead Sponsor:

GE Healthcare

Conditions:

Breast Cancer

Tumors, Breast

Eligibility:

FEMALE

30+ years

Phase:

NA

Brief Summary

The aim of this recruitment plan (ADAPT-SCR) is to collect image and other data on both digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) from asymptomatic women undergoing ...

Detailed Description

ADAPT program consists of 2 recruitment plans (ADAPT-SCR and ADAPT-BX) followed by an off-line read of the images and data collected (ADAPT-BIE). This study involves the comparison of two devices that...

Eligibility Criteria

Inclusion

  • Women aged 30 years or older (≥30 years old);
  • Asymptomatic women scheduled for screening mammography or have completed a screening mammogram within the past 30 days;
  • Mammography completed on a General Electric (GE) GE FFDM system (with craniocaudal (CC) and mediolateral oblique (MLO) views) at the site or another clinical facility;
  • Are able and willing to comply with study procedures;
  • Have signed and dated the informed consent form;
  • Are either surgically sterile or postmenopausal or, if of childbearing potential, the possibility of pregnancy is remote based on a documented negative patient history and, optionally, a negative urine pregnancy test (if subject requests one).

Exclusion

  • Have been previously included in this study;
  • Have a history of breast cancer and are in active treatment. However, subjects with a prior lumpectomy (\> 5 years prior) who receive only routine screening mammography views can be included;
  • Have breasts too large to be adequately positioned on 24 x 31 centimeter (cm) FFDM digital receptor without anatomical cut off during either FFDM or DBT examination;
  • Have participated in (within the prior 30 days) another trial of an investigational product expected to interfere with study procedures or outcomes;
  • Have breast implant(s);
  • Have reconstructed breast(s).

Key Trial Info

Start Date :

May 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 7 2017

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT02306265

Start Date

May 1 2015

End Date

July 7 2017

Last Update

January 29 2019

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Beaumont Health System

Royal Oak, Michigan, United States, 48073

2

Allegheny General Hospital

Pittsburgh, Pennsylvania, United States, 15212