Status:

TERMINATED

Efficacy and Safety of Vatelizumab in Patients Who Completed Treatment in Study DRI13839

Lead Sponsor:

Genzyme, a Sanofi Company

Conditions:

Relapsing-remitting Multiple Sclerosis

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Primary Objective: To assess the long-term safety of vatelizumab in MS patients Secondary Objective: To assess the long-term efficacy of vatelizumab

Detailed Description

The maximum study duration per patient will be 192 weeks, including a Treatment Period of 96 weeks and Post-treatment Safety Follow-up Period of 96 weeks.

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Patients who completed the 12-week treatment period in DRI13839.
  • Exclusion criteria:
  • Any clinically significant or ongoing adverse events, or laboratory abnormalities from DRI13839 that per Investigator judgment would adversely affect the patient's participation in the long-term extension study.
  • Confirmed platelet count below the lower limit of normal at any time during DRI13839.
  • Pregnancy or breast-feeding.
  • Other protocol defined exclusion criteria may apply.
  • The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

Exclusion

    Key Trial Info

    Start Date :

    February 1 2015

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    July 1 2016

    Estimated Enrollment :

    62 Patients enrolled

    Trial Details

    Trial ID

    NCT02306811

    Start Date

    February 1 2015

    End Date

    July 1 2016

    Last Update

    December 21 2016

    Active Locations (18)

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    Page 1 of 5 (18 locations)

    1

    Investigational Site Number 840004

    Cullman, Alabama, United States, 35058

    2

    Investigational Site Number 840005

    Fort Collins, Colorado, United States, 80528

    3

    Investigational Site Number 840007

    Ormond Beach, Florida, United States, 32174

    4

    Investigational Site Number 840001

    Latham, New York, United States, 12210