Status:
UNKNOWN
Effect of Smoking Reduction on Endothelial Glucocalyx and Vascular Function
Lead Sponsor:
University of Athens
Conditions:
Smoking Cessation
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The integrity of endothelial glucocalyx plays a vital role in vascular permeability and inflammation. Smoking cessation is related with improved vascular function and is a key component of secondary c...
Detailed Description
The investigators will examine smokers without cardiovascular disease treated with transdermal nicotine patches and/or varenicline at before, 4, 12, 24 and 48 weeks after treatment during validated sm...
Eligibility Criteria
Inclusion
- Smokers
Exclusion
- Coronary artery disease
- Heart failure
- Diabetes mellitus
- Dyslipidemia
Key Trial Info
Start Date :
December 3 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2020
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT02307045
Start Date
December 3 2014
End Date
December 1 2020
Last Update
April 3 2020
Active Locations (1)
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1
''Attikon'' University General Hospital
Athens, Attica, Greece, 12462