Status:

WITHDRAWN

SPECTAbrain: Screening Patients With Brain Tumors for Efficient Clinical Trial Access

Lead Sponsor:

European Organisation for Research and Treatment of Cancer - EORTC

Conditions:

Brain Neoplasms

Eligibility:

All Genders

18+ years

Brief Summary

The SPECTAbrain protocol describes a structure for screening patients with brain tumors to efficiently allocate eligible patients in relevant therapeutic biomarker-driven clinical trials. Efficiency i...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Pathologically confirmed newly diagnosed primary CNS tumors, with a focus on diffuse gliomas of grades II, III and IV, meningiomas from patients who are candidates for pharmacotherapy, and rare CNS tumors;
  • Availability of adequate Human Biological Material (HBM): FFPE tissue sample from the primary and/or recurrent tumor and/or metastasis, obtained at the time of surgery or biopsy; minimal amount requested is detailed in the HBM guidelines. Inclusion of samples taken at any recurrence diagnosed during follow-up is strongly encouraged but optional;
  • At least three months life expectancy;
  • Written informed consent according to ICH/GCP and national/local regulations;
  • Absence of exclusion criteria, such as active hepatitis B/C or HIV, second malignancies, severe organ dysfunction, or other comorbidities that will prevent inclusion into clinical trials.

Exclusion

    Key Trial Info

    Start Date :

    May 1 2016

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    January 1 2019

    Estimated Enrollment :

    Patients enrolled

    Trial Details

    Trial ID

    NCT02307604

    Start Date

    May 1 2016

    End Date

    January 1 2019

    Last Update

    June 24 2019

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    CHRU de Lille

    Lille, France, FR 59037

    2

    Assistance Publique - Hopitaux de Paris - La Pitie Salpetriere

    Paris, France, FR 75651