Status:

COMPLETED

Treatment and Prognosis of Neurogenic Orthostatic Hypotension : A Prospective Randomized Study

Lead Sponsor:

Seoul National University Hospital

Conditions:

Orthostatic; Hypotension, Neurogenic

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Compare the effect of treatment of midodrine and pyridostigmine in neurogenic orthostatic hypotension and investigate the quality of life of treatment of neurogenic orthostatic hypotension.

Detailed Description

In patients with neurogenic orthostatic hypotension, the appropriate treatment was identified by comparing the treatment effects and side effects for each treatment drug. In addition, by confirming th...

Eligibility Criteria

Inclusion

  • age \>=18 patients who complained of dizziness
  • Orthostatic hypotension after 3-minute standing (systolic blood pressure drop \>=20 or diastolic blood pressure drop \>=10

Exclusion

  • Drug-induced hypotension, if necessary, evaluate patient after discontinuing the causative drug for one month
  • Heart failure or Chronic renal failure
  • Patients who cannot or do not want to write questionaires.
  • Poor drug compliance

Key Trial Info

Start Date :

November 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2016

Estimated Enrollment :

87 Patients enrolled

Trial Details

Trial ID

NCT02308124

Start Date

November 1 2014

End Date

September 1 2016

Last Update

October 19 2021

Active Locations (1)

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Seoul National University Hospital

Seoul, South Korea