Status:

UNKNOWN

Impaired Secretory IgA and Mucosal Immunity in Cystic Fibrosis

Lead Sponsor:

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

18+ years

Brief Summary

This project entitled "Impaired secretory IgA and mucosal immunity in cystic fibrosis" is a research program which aims to determine, owing to national (KULeuven) and international (Descartes universi...

Detailed Description

Impaired secretory IgA and mucosal immunity in cystic fibrosis: role of CFTR-related epithelial changes in the regulation of pIgR-mediated IgA transcytosis and contribution to lung pathology and impa...

Eligibility Criteria

Inclusion

  • CF: adult CF patients (from age 18) with a classical clinical phenotype related to DF508/DF508 mutation, and colonized or not with Pseudomonas aeruginosa

Exclusion

  • \<18 years
  • other chronic lung diseases except COPD as a specific control subgroup

Key Trial Info

Start Date :

November 1 2015

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2017

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT02308267

Start Date

November 1 2015

End Date

December 1 2017

Last Update

February 25 2016

Active Locations (1)

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1

StLuc

Brussels, Belgium, 1200