Status:

COMPLETED

Centralized Reading Assessment of Chronic CerebroSpinal Venous Insufficiency (CCSVI) in Patients With Multiple Sclerosis and Other Neurological Diseases

Lead Sponsor:

University at Buffalo

Collaborating Sponsors:

University of Pavia

Conditions:

Clinically Isolated Syndrome (CIS)

Multiple Sclerosis (MS)

Eligibility:

All Genders

5-80 years

Brief Summary

This a retrospective, blinded trial in which collaborators in Italy will review the doppler findings from the Combined Transcranial and Extracranial Venous Doppler (CTEVD) trial in an attempt to measu...

Detailed Description

This study will retrospectively investigate doppler images from the second phase of the CTEVD trial. 1. To determine the prevalence of CCSVI in patients with MS, compared with the prevalence observed...

Eligibility Criteria

Inclusion

  • Participation in the CTEVD Phase 2 study
  • Available CDUS exam
  • Diagnosed with CIS, MS, OND, or being a HC
  • Fulfilling inclusion criteria from the CTEVD study

Exclusion

  • Not having an available CDUS exam
  • Diagnosed with Radiologically Isolated Syndrome (RIS) or Neuromyelitis Optic (NMO)
  • Fulfilling exclusion criteria from the CTEVD study

Key Trial Info

Start Date :

July 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2015

Estimated Enrollment :

499 Patients enrolled

Trial Details

Trial ID

NCT02308579

Start Date

July 1 2014

End Date

March 1 2015

Last Update

February 12 2016

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