Status:
COMPLETED
Oral Astaxanthin and Semen Quality, Fertilization and Embryo Development in Assisted Reproduction Techniques Procedures
Lead Sponsor:
University Medical Centre Ljubljana
Conditions:
Infertility, Male
Eligibility:
MALE
18+ years
Phase:
NA
Brief Summary
The purpose of the study is to determine whether administration of dietary supplement of astaxanthin with vitamin E improves the quality of sperm, fertilization and embryo development in Assisted Repr...
Detailed Description
In the study male patients diagnosed with oligoasthenozoospermia - with an abnormal sperm concentration and motility, irrespective of the morphology of spermatozoa - treated with their female partner ...
Eligibility Criteria
Inclusion
- oligoasthenozoospermia with of without teratozoospermia by WHO criteria from the year 2010
- fresh semen
- female partner younger than 38 years
- idiopathic or tubal infertility in female partners
- at least 4 oocytes retrieved in previous ovarian punction in ART cycle, if previously performed
- 1st, 2nd or 3rd cycle of ART
Exclusion
- genetic indication for ART procedure
- donated semen
- polycystic ovary syndrome in female partner
- dietary supplementation intake of antioxidants (selenium, zink, vitamin E, vitamin C, vitamin A) in male participant in the last three months
- smoking in male participant \>20 cigarettes per day
Key Trial Info
Start Date :
November 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2019
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT02310087
Start Date
November 1 2014
End Date
January 1 2019
Last Update
March 29 2019
Active Locations (1)
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1
Division of Ob/Gyn, University Medical Centre Ljubljana
Ljubljana, Slovenia, 1000