Status:
RECRUITING
Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion
Lead Sponsor:
Imperial College London
Conditions:
Cancer
Rectal Cancer
Eligibility:
All Genders
16+ years
Brief Summary
This study does not involve randomization or treatment. Eligible patients have colorectal adenocarcinoma with no metastases eligible for curative surgery. A pre operative staging scan must have been c...
Detailed Description
A multicentre observational study, ctDNA aims to provide the evidence base for metatstatic disease being caused by vascular methods of spread by determining if there is a link between EMVI status and ...
Eligibility Criteria
Inclusion
- Have a biopsy-confirmed colorectal adenocarcinoma
- Is eligible for curative surgery
- Has no metastatic disease on CT scan
- Has completed pre-operative staging scan within six weeks prior to surgery
- Have provided written informed consent to participate in the study
- Be aged 16 years or over
Exclusion
- Have metastatic disease (including resectable liver metastases)
- Have a synchronous second malignancy
- Are contraindicated for any imaging able to determine EMVI status
Key Trial Info
Start Date :
November 1 2015
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2029
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT02579278
Start Date
November 1 2015
End Date
December 1 2029
Last Update
October 17 2024
Active Locations (3)
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1
Queen Elizabeth the Queen Mother Hospital
Margate, Kent, United Kingdom, CT9 4AN
2
St Mary's Hospital (Imperial)
Hammersmith, London, United Kingdom, W2 1NY
3
Royal Marsden Hospital NHS Foundation Trust
Sutton, Surrey, United Kingdom, SM2 5PT