Status:
COMPLETED
Efficacy of Different Perioperative Statin Regimens on the Protection Against Post Coronary Artery Bypass Grafting Major Adverse Cardio-cerebral Events
Lead Sponsor:
Cairo University
Conditions:
Coronary Artery Bypass Grafting
Eligibility:
All Genders
42-71 years
Phase:
PHASE4
Brief Summary
This study aims at comparing different perioperative statin regimens for the prevention of post CABG adverse events. This was a randomized, prospective clinical trial. Ninety four patients scheduled ...
Detailed Description
This study was conducted at the National Heart Institute (NHI), Cairo, Egypt, during the period between June 2013 and February 2015. It was approved by the ethics committee at the Faculty of Pharmacy,...
Eligibility Criteria
Inclusion
- Ischemic Heart Disease patients referred for elective isolated on- or off- pump CABG
- Adult patients with normal preoperative hemoglobin, hematocrit, albumin, cardiac markers; Cardiac troponin I (TnI) and Creatine Kinase-MB (CK-MB) levels.
- Serum creatinine \< 2 mg/dl and aspartate aminotransferase (AST) and alanine aminotransferase (ALT) \< 3 times upper normal limit (UNL).
Exclusion
- Recent history of stroke, myocardial infarction (MI), atrial fibrillation (AF) or any other type of arrhythmias.
- Any malignancy, inflammatory or muscle disease were not included in this study.
- Hypersensitivity to statins or on medications that are known to interact with statins.
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2015
Estimated Enrollment :
94 Patients enrolled
Trial Details
Trial ID
NCT02706860
Start Date
June 1 2013
End Date
February 1 2015
Last Update
March 14 2016
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