Status:

COMPLETED

Assessment of the Impact of Probiotics on Biofilm Formation on Removable Acrylic Dentures

Lead Sponsor:

Universitaire Ziekenhuizen KU Leuven

Conditions:

Mandibular Prosthesis User

Eligibility:

All Genders

Phase:

NA

Brief Summary

The aim of this study is to evaluate the effect of PIP toothbrush cleaner® on the microbial composition and Candida albicans colonization of denture biofilm formation. Additionally, its effect will be...

Detailed Description

Therefore the present study intended to compare a probiotic denture cleaning protocol with the current protocols. It was aimed to examine, in institutionalized older individuals with removable complet...

Eligibility Criteria

Inclusion

  • Reside in a home for elderly
  • Fully edentulous in lower and upper jaw
  • Removable denture wearer in lower and upper jaw
  • Good oral health

Exclusion

  • Current or history of corticosteroid treatment within the 3 months prior to the study
  • Current or history of antimicrobial treatment within the 3 months prior to the study
  • Inability to provide informed consent
  • Inability to comply with the study requirements
  • Heart disorders persons with a high risk for an unfavourable prognosis of bacterial endocarditis will be excluded. This applies to patients with prosthetic heart valves, history of infectious endocarditis, cyanogenic congenital heart disorders (including palliative shunts and connections), completely recovered congenital disorders that were treated less than 6 months ago, treated congenital heart disorders with residual defect, and valvulopathy after heart transplantation.

Key Trial Info

Start Date :

April 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2014

Estimated Enrollment :

13 Patients enrolled

Trial Details

Trial ID

NCT02736994

Start Date

April 1 2014

End Date

September 1 2014

Last Update

April 13 2016

Active Locations (1)

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Department of Oral Health Sciences

Leuven, Belgium, 3000