Status:
COMPLETED
Dietary Reduction of AGEs to Prevent Cognitive Decline in Elderly Diabetics
Lead Sponsor:
Sheba Medical Center
Collaborating Sponsors:
Hebrew University of Jerusalem
Conditions:
Cognitive Decline
Aging
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
Basic science and observational human studies suggest that high conentrations of circulating Advanced Glycation End-products (AGEs) may promote cognitive decline in older adults. The purpose of this p...
Eligibility Criteria
Inclusion
- Above the age 65
- T2D diagnosis
- no dementia (i.e MCI or cognitively normal )
- Not receiving cholinesterase inhibitors
- No other neurological (e.g. stroke, Parkinson's disease) or psychiatric conditions (e.g. schizophrenia, depression) that may affect cognition
- Dietary AGE levels \> 13kU
- Not participating in another clinical trial
- An informant that is willing to actively support the participant throughout the study
- Exclusion Criteria:
- Dementia
- Stroke
- Other major neuropsychiatric condition that might affect cognition
Exclusion
Key Trial Info
Start Date :
June 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2020
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT02739971
Start Date
June 1 2016
End Date
June 1 2020
Last Update
March 23 2021
Active Locations (1)
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1
Joseph Sagol Neuroscience center, Sheba Medical Center
Ramat Gan, Israel