Status:

COMPLETED

A Non-interventional Study on Xarelto for Treatment of Venous Thromboembolism (VTE) and Prevention of Recurrent VTE in Patients With Active Cancer

Lead Sponsor:

Bayer

Collaborating Sponsors:

Janssen Research & Development, LLC

Conditions:

Venous Thrombosis and Pulmonary Embolism

Eligibility:

All Genders

18+ years

Brief Summary

This study aims to collect patient reported outcomes and assess treatment satisfaction in active cancer patients treated with rivaroxaban for VTE (venous thromboembolism).

Eligibility Criteria

Inclusion

  • Adult female and male patients with active cancer other than fully treated basal-cell or squamous-cell carcinoma of the skin (active cancer defined as the diagnosis or treatment of cancer in the previous \< 6 months or recurrent or metastatic cancer)
  • Patients that have been treated with standard of care anticoagulation (Low Molecular Weight Heparin / Vitamin K Antagonist) for treatment of DVT and/ or PE (index VTE event) and/ or prevention of recurrent DVT and PE for at least 4 weeks prior to inclusion in the study
  • Patients for whom the decision was made to start rivaroxaban for treatment of DVT and/ or PE and/ or prevention of recurrent DVT and PE
  • Patients with Eastern Cooperative Oncology Group (ECOG) performance status score of 0, 1 or 2
  • Patients who are willing to participate in this study (signed informed consent)
  • Patients who are available for follow-up with a life expectancy \>6 months

Exclusion

  • The contra-indications according to the local marketing authorization must be considered
  • Patients who developed an index VTE event despite chronic anticoagulant therapy
  • Patients receiving apixaban, edoxaban or dabigatran or any investigational drug as the initial therapy for the index VTE event
  • Patients participating in an investigational program with interventions outside of routine clinical practice with exception of oncology investigational trials

Key Trial Info

Start Date :

October 11 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 28 2019

Estimated Enrollment :

528 Patients enrolled

Trial Details

Trial ID

NCT02742623

Start Date

October 11 2016

End Date

March 28 2019

Last Update

November 7 2023

Active Locations (10)

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Page 1 of 3 (10 locations)

1

Multiple Locations, Australia

2

Multiple Locations, Belgium

3

Multiple Locations, Canada

4

Multiple Locations, Denmark

A Non-interventional Study on Xarelto for Treatment of Venous Thromboembolism (VTE) and Prevention of Recurrent VTE in Patients With Active Cancer | DecenTrialz