Status:

UNKNOWN

The Clinical Relevance of P16 Expressing CTCs Detection Comparing With HPV Infection in Cancer Tissue in HNSCC Patients.

Lead Sponsor:

Chang Gung Memorial Hospital

Conditions:

Recurrence

Metastasis

Eligibility:

All Genders

20+ years

Brief Summary

HNSCC is the 4th highest incidence of cancer and 6th of cancer death of the males in Taiwan. Because the patients were mainly middle-aged male, the disease eventually resulted in a huge loss of labor ...

Detailed Description

1. Establish a protocol and a practical platform to longitudinally isolate, enumerate CTCs in patients with HPV+-head and neck cancer during the treatment course. 2. Elucidate the clinical significanc...

Eligibility Criteria

Inclusion

  • histologically or cytopathologically proven head and neck squamous cell carcinoma Age ≥ 20 years. Measurable or evaluable disease according to Response Evaluation Criteria In Solid Tumors(RECIST) criteria.
  • Ability to sign informed consent.

Exclusion

  • Prior cancers within 5 years, except for non-melanoma skin cancers, and in situ cervical cancers.
  • Inability to completely with study and/or follow-up procedures.

Key Trial Info

Start Date :

July 1 2015

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2019

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT02791607

Start Date

July 1 2015

End Date

June 1 2019

Last Update

August 10 2017

Active Locations (1)

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Chang Gung Memorial Hospital

Taoyuan District, Taiwan, 333