Status:
ACTIVE_NOT_RECRUITING
New Approaches in MRI at 3T Dedicated to Targeting Subthalamic Nucleus on Parkinsonian Patients
Lead Sponsor:
Institut National de la Santé Et de la Recherche Médicale, France
Conditions:
Parkinson Disease
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a validated procedure, used in many French and international centers for the treatment of severe forms of Parkinson's disease (PD). The...
Detailed Description
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a validated procedure, used in many French and international centers for the treatment of severe forms of Parkinson's disease (PD). The...
Eligibility Criteria
Inclusion
- Diagnosis of idiopathic Parkinson's disease (according to the criteria of the "United Kingdom Parkinson's Disease Society Brain Bank";
- Age between 18 and 70 years
- motor complications in the form of fluctuations in motor state or induced dyskinesias dopaminergic therapy, despite optimal medical treatment;
- Excellent responsiveness to levodopa (improved motor UPDRS score of higher than 50% during the acute test with levodopa)
- People who voluntarily accepted and intelligently participate in the study (signing a written consent)
- Patient receiving social health insurance
Exclusion
- Patients carry an apomorphine pump used in single and continuous treatment;
- scalable psychiatric pathology;
- Dementia (MMS \<24/30);
- Existence of against-indications to MRI (cardiac or neural stimulator, ferromagnetic surgical clips, implants and metal objects, intraocular foreign bodies, pregnancy, claustrophobia).
- Persons under guardianship, trusteeship or any other administrative or judicial deprivation of rights and freedom
Key Trial Info
Start Date :
October 12 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 7 2025
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT02800460
Start Date
October 12 2016
End Date
December 7 2025
Last Update
August 8 2025
Active Locations (1)
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1
GHPS
Paris, Île-de-France Region, France, 75651