Status:
COMPLETED
Gene Expression and Biomarker Profiling of Keloid Skin
Lead Sponsor:
Northwestern University
Collaborating Sponsors:
Regeneron Pharmaceuticals
Conditions:
Keloid
Keloid of Ear Lobe
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study aims to examine both the genetic profile and the biomarkers implicated in keloid scar formation. Hypothesis: 1. Differences in the genetic profiles of lesional and non-lesional skin contr...
Detailed Description
Objectives: 1. Determine gene expression profiles of keloid scar tissue using samples collected longitudinally 2. Define and compare the molecular biomarkers of keloid scars in keloid (lesional) and ...
Eligibility Criteria
Inclusion
- Patient with an untreated keloid scar or a patient with a keloid scar that has not had treatment for at least 6 months before time of enrollment
- Patients without keloids coming into the dermatology clinic for a keloid unrelated issue (Group 5 only)
Exclusion
- Patients who have had treatment of their keloid scar within 6 months of date of enrollment
Key Trial Info
Start Date :
September 11 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2023
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT03228693
Start Date
September 11 2017
End Date
January 31 2023
Last Update
March 29 2023
Active Locations (1)
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1
Northwestern University Feinberg School of Medicine Department of Dermatology
Chicago, Illinois, United States, 60611