Status:
COMPLETED
Xylitol for Chronic Sinusitis
Lead Sponsor:
Ochsner Health System
Collaborating Sponsors:
Tulane University School of Medicine
Conditions:
Chronic Rhinosinusitis
Rhinosinusitis
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this investigation is to conduct a randomized controlled trial within a subgroup of difficult-to-treat patients with CRS, evaluating the use of topical xylitol treatment concurrently wi...
Detailed Description
Problem Statement: The purpose of this investigation is to conduct a trial within a subgroup of difficult-to-treat patients with CRS. This difficult group of patients will have undergone an exhaustiv...
Eligibility Criteria
Inclusion
- Adult patients above the age of 18
- History of chronic rhinosinusitis history who had undergone bilateral endoscopic sinus surgery to include at a minimum maxillary antrostomy and anterior ethmoidectomy.
- Continued chronic sinusitis that is refractory to medical therapy after surgical intervention
Exclusion
- Patients under age of 18
- Non-English speaking
- History of immunodeficiency disease
- Cystic fibrosis
- Primary ciliary dyskinesia
- History of granulomatous disease
- Active smoker
- Treatment with antifungal medications
- Use of antifungal medications
- Acute bacterial infection requiring antibiotics
- Active pregnancy
Key Trial Info
Start Date :
March 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 16 2018
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT03229551
Start Date
March 1 2018
End Date
July 16 2018
Last Update
April 7 2023
Active Locations (1)
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1
Ochsner Medical Center
New Orleans, Louisiana, United States, 70121