Status:
UNKNOWN
Computerized Cognitive Training for MCI
Lead Sponsor:
Peking University
Conditions:
Mild Cognitive Impairment
Eligibility:
All Genders
60-89 years
Phase:
NA
Brief Summary
The objective of the study is to evaluate whether memory training combined with executive training could lead to improved cognitive and noncognitive performance in patients with MCI. Furthermore, we w...
Detailed Description
Introduction: Mild cognitive impairment (MCI) is a clinical condition characterized of a reduction in memory and/or other cognitive processes that are insufficiently severe to be diagnosed as dementi...
Eligibility Criteria
Inclusion
- An objective cognition impairment (a Montreal Cognitive Assessment (MoCA) score \< 26)
- Preserved general cognitive function( an mini-mental state examination (MMSE) score of \> 24)
- Clinical Dementia Rating (CDR) = 0.5
- Hamilton Depression Scale (HAMD) score of \< 12
- Intact activities of daily living (ADL score of \<=26)
- Schooling education \> = 5 years)
- Not meeting the diagnosis of dementia (according to the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) and the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) Probable Alzheimer's Criteria
Exclusion
- Serious visual or hearing impairment;
- Hachinski Ischemia Scale (HIS) \>= 4;
- Subjects with Axis I disorders listed in the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV), any other neurological disorders that could affect cognitive function;
- currently on titration of medications with cognitive enhancers or antidepressants;
- having any physical condition that could preclude regular attendance and full intervention-program participation
Key Trial Info
Start Date :
August 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2019
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03232047
Start Date
August 1 2017
End Date
December 31 2019
Last Update
March 21 2019
Active Locations (1)
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1
Peking University Institute of Mental Health(Six Hospital)
Beijing, Beijing Municipality, China, 100191