Status:

COMPLETED

Effects of Altitude on Single-Breath Diffusing Capacity for Carbon Monoxide

Lead Sponsor:

Intermountain Health Care, Inc.

Collaborating Sponsors:

University of Utah

Conditions:

COPD

Eligibility:

All Genders

20-80 years

Brief Summary

The purpose of this study is to further understand the effects of altitude on the physiology of gas exchange in the pulmonary microcirculation in normal subjects and in people with chronic obstructive...

Detailed Description

The DLCOsb is one of the most common and widely tests clinically used across the world in pulmonary function laboratories to assess gas exchange from the lung to hemoglobin in the pulmonary circulatio...

Eligibility Criteria

Inclusion

  • Ages 20- 80 years
  • Subjects must be either healthy or have been diagnosed with COPD

Exclusion

  • Anemia (hemoglobin \< 10.0 g/dL)
  • Carboxyhemoglobin \> 3%
  • Active smoking
  • Heart disease or heart failure
  • Pulmonary hypertension
  • COPD exacerbation
  • Pneumothroax within 6 months
  • Bullous emphysema on chest imaging (Chest X-ray or CT)
  • Supplemental oxygen use
  • Diabetes mellitus
  • Alcohol dependence
  • Non-English speaking

Key Trial Info

Start Date :

August 10 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 1 2019

Estimated Enrollment :

23 Patients enrolled

Trial Details

Trial ID

NCT03235297

Start Date

August 10 2017

End Date

July 1 2019

Last Update

February 12 2020

Active Locations (1)

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Intermountain Medical Center

Murray, Utah, United States, 84157