Status:
COMPLETED
Normal Liver Stiffness by MR Elastography
Lead Sponsor:
Children's Hospital Medical Center, Cincinnati
Collaborating Sponsors:
Massachusetts General Hospital
Washington University School of Medicine
Conditions:
Liver Diseases
Eligibility:
All Genders
7-17 years
Phase:
NA
Brief Summary
Healthy children will be recruited to under Magnetic Resonance Imaging (MRI)along with MR elastography to determine normal liver stiffness values.
Detailed Description
MR elastography (MRE) is playing a growing role in the non-invasive diagnosis and monitoring of liver disease in the pediatric population. There is, however, little data specific to the use of this te...
Eligibility Criteria
Inclusion
- Age 7-17 years
- No documented history of liver diseases
- English speaking
Exclusion
- NPO less than 4 hours
- Body mass index \<10th or \> 85th percentile for age
- Documented history of liver disease
- Pregnancy
- Inability to lie still for duration of the MRI
- Inability to breath hold for the duration of the 15-20 second MR elastography sequence
- Standard contraindication to MRI (implanted hardware, etc.)
- Requirement of sedation or general anesthesia for MRI
- Abnormality of any measured liver function test
- Liver fat fraction \>5% by MRI PDFF
Key Trial Info
Start Date :
February 19 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 24 2020
Estimated Enrollment :
101 Patients enrolled
Trial Details
Trial ID
NCT03235414
Start Date
February 19 2018
End Date
July 24 2020
Last Update
September 16 2020
Active Locations (1)
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1
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229