Status:

UNKNOWN

The Gut-lung Axis in Chronic Obstructive Pulmonary Disease

Lead Sponsor:

Peking University People's Hospital

Collaborating Sponsors:

Ningde City Hospital, Fujian, China

Conditions:

Pulmonary Disease, Chronic Obstructive

Microbiota

Eligibility:

All Genders

40+ years

Brief Summary

Patients with chronic obstructive pulmonary disease (COPD) are 2-3 times more likely to occur together with chronic gastrointestinal tract (GIT) diseases, such as inflammatory bowel disease (IBD) or i...

Eligibility Criteria

Inclusion

  • admitted to hospital with an exacerbation of COPD;
  • with no history of probiotics taken;
  • the duration of antibiotics treatment before enrollment should be less than 72 hours.

Exclusion

  • being immunocompromised, including history of glucocorticoid taken for more than 1 month, history of immunosuppressive therapy, history of human immunodeficiency virus (HIV) infection, solid tumor or hematological malignancy;
  • history of long-term nursing home stays;
  • history of recently hospitalized (\<90 days).

Key Trial Info

Start Date :

January 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2019

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT03236480

Start Date

January 1 2017

End Date

January 1 2019

Last Update

August 2 2017

Active Locations (1)

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Peking University People's Hospital

Beijing, Beijing Municipality, China, 100044