Status:

TERMINATED

Real Time Amplitude Spectrum Area to Guide Defibrillation

Lead Sponsor:

Mario Negri Institute for Pharmacological Research

Collaborating Sponsors:

European Commission

Zoll Medical Corporation

Conditions:

Out-Of-Hospital Cardiac Arrest

Ventricular Fibrillation

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

AMSA trial is a multicenter, randomized, controlled study in out-of-hospital cardiac arrest patients. The purpose of the study is to test the hypothesis that a real time AMSA analysis during CPR may ...

Detailed Description

In the AMSA-CPR intervention, upon arrival of the advanced life support (ALS) rescue team at the cardiac arrest scene and application of the defibrillatory pads to the patient's chest and power on of ...

Eligibility Criteria

Inclusion

  • All adult patients (age ≥ 18) suffering of out-of-hospital non traumatic cardiac arrest of presumably cardiac etiology with a presenting shockable rhythm requiring electrical defibrillation: Ventricular Fibrillation and pulseless Ventricular Tachycardia.

Exclusion

  • age \< 18 years old
  • pregnancy
  • cardiac arrest with a non-shockable rhythm (pulseless electrical activity and asystole)
  • a defibrillation delivered by an AED prior to ALS arrival
  • cardiac arrest of traumatic origin
  • non-cardiac cause of cardiac arrest
  • presumable irreversible death or known terminal illness at the beginning of ALS
  • clinical death
  • participation in another clinical or device trial within the previous 30 days
  • refused informed consent to the use of data.

Key Trial Info

Start Date :

April 28 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 26 2021

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT03237910

Start Date

April 28 2019

End Date

July 26 2021

Last Update

October 3 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

UOC Rianimazione-Emergenza Territoriale 118, Dipartimento di Emergenza, Ospedale Maggiore - AUSL di Bologna

Bologna, Italy, 40124

2

SOREU Metropolitana - AREU ASST, Grande Ospedale Metropolitano Niguarda

Milan, Italy, 20162