Status:

COMPLETED

Chemotherapy / Radiotherapy in Uterine Cervical Neoplasms

Lead Sponsor:

Instituto Nacional de Cancerologia, Columbia

Conditions:

Uterine Cervical Neoplasms

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Compare the use of radiotherapy and concomitant chemotherapy, with the single use of radiotherapy in the treatment of patients with stage IIIB uterine cancer, having as an outcome the three year survi...

Detailed Description

Inclusion criteria Women between 18 and 80 years old, diagnosed with uterine squamous cell cancer or stage IIIB adenocarcinoma (FIGO) with ECOG equal 1 or less and a Karnofsky equal or more than 70%. ...

Eligibility Criteria

Inclusion

  • Women between 18 and 80 years old, diagnosed with uterine squamous cell cancer or stage IIIB adenocarcinoma (FIGO) with ECOG equal 1 or less and a Karnofsky equal or more than 70%.

Exclusion

  • Having a concomitant or previous neoplasia, except for patients with skin tumors not associated to melanomas, platelet count under 100.000, hemoglobin levels of 10 gr/dl or above before starting the first radiotherapy session, patients with recurrent invasive uterine carcinoma, patients with compromised para aortic lymph nodes, patients with active and non controlled pelvic infection by the beginning of the treatment, creatinine depuration less than 45 ml/min confirmed with glomerular filtration rate less than 45 ml/min, neutrophils count less than 1,500/ml, and pregnant or nursing woman.

Key Trial Info

Start Date :

August 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2016

Estimated Enrollment :

147 Patients enrolled

Trial Details

Trial ID

NCT03238261

Start Date

August 1 2007

End Date

May 1 2016

Last Update

August 11 2017

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