Status:
UNKNOWN
A Study to Determine the Clinical Characteristics, Comorbidities, Treatment Status and Exacerbations of Asthma Patients
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Asthma
Eligibility:
All Genders
18+ years
Brief Summary
This is a prospective cohort study that aims to determine the current demographics, clinical characteristics, comorbidities, treatment status and exacerbations of asthma patients. The primary objecti...
Detailed Description
Asthma is a common respiratory disease worldwide and in Hong Kong. According to the estimation by the Center for Disease Control and Prevention in 2015, 7.6% adults in the United States have asthma. I...
Eligibility Criteria
Inclusion
- All patients with confirmed diagnosis of asthma (defined as those with a consistent history and prior documented evidence of variable airflow obstruction, with evidence of an increase in FEV1 greater than 12% or 200 mL following bronchodilator or bronchial hyperresponsiveness on bronchial provocation testing, when stable (reference)
- Age greater than 18 years old
- Signed written informed consent to participate in the study
Exclusion
- Patients currently with acute exacerbation of asthma by GINA guideline (they can join the study after 6 weeks post recovery from the exacerbation)
- Patients with respiratory diseases that can show similar symptoms to asthma such as bronchiectasis, tuberculosis-destroyed lung parenchyma, endobronchial TB, and lung cancer, or those who have history of these diseases based on physician's judgment
- Patients with respiratory diseases that may confound the lung function parameters such as pleural diseases, interstitial lung diseases, and previous lung surgery, or those who have history of these diseases based on physician's judgment
- Patients with neuromuscular diseases that may affect the seal off the mouthpiece during spirometry and forced oscillometry technique (FOT)
- Patients with uncontrolled or active contagious respiratory infection diseases
- Patients with smoking history more than 10 pack years
- Significant comorbid illnesses that limit the life expectancy to less than 1 year
- Patients who are mentally not fit or physically contraindicated for spirometry and FOT
- Patients with psychiatric disease or cognitive impairment that may limit their ability of understanding or giving consent to the study
- Patients currently randomized in other clinical studies
Key Trial Info
Start Date :
September 15 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 31 2022
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT03239431
Start Date
September 15 2017
End Date
January 31 2022
Last Update
January 31 2019
Active Locations (1)
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1
Chinese University of Hong Kong
Hong Kong, Hong Kong