Status:
COMPLETED
Modern Pain Neuroscience Applied to Chronic Pain in Patients With Chronic Whiplash Associated Disorders
Lead Sponsor:
Vrije Universiteit Brussel
Collaborating Sponsors:
University Hospital, Ghent
University Ghent
Conditions:
Whiplash
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Modern pain neuroscience has advanced our understanding of chronic whiplash associated disorders (WAD). Previous studies have shown the importance of central sensitization, characterized by hypersensi...
Detailed Description
Modern pain neuroscience has advanced our understanding of chronic whiplash associated disorders (WAD). Previous studies have shown the importance of central sensitization, characterized by hypersensi...
Eligibility Criteria
Inclusion
- Experienced a whiplash trauma which is at least 3 months old and causes pain since at least 3 months, with pain experience with a mean pain frequency of 3 or more days per week, and with self-reported moderate to severe pain-related disability, established by a score of 15 or more of a maximum of 50 on the Neck Disability Index
- Patients classified as WAD II or WAD III on the modified Quebec Task Force Scale
- Native Dutch speaker
- Not starting new treatments or medication and continuing their usual care 6 weeks prior to and during study participation (to obtain a steady state)
- Refraining from non-opioid analgesics in the previous 48h of the assessments
- Refraining from caffeine, alcohol, and nicotine in the previous 24h of the assessments
Exclusion
- Neuropathic pain
- Being pregnant or having given birth in the preceding year
- Chronic fatigue syndrome
- Fibromyalgia
- Cardiovascular disorders
- Epilepsy
- Endocrinological disorders
- Rheumatic disorders
- Psychiatric disorders
- History of neck surgery
- Loss of consciousness during/after the whiplash trauma
- Post-traumatic amnesia
Key Trial Info
Start Date :
August 17 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 13 2022
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03239938
Start Date
August 17 2017
End Date
June 13 2022
Last Update
November 28 2022
Active Locations (3)
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1
Sint-jozefkliniek Campus Bornem (AZ Rivierenland)
Bornem, Antwerpen, Belgium, 2880
2
Ghent University
Ghent, Oost-Vlaanderen, Belgium, 9000
3
Vrije Universiteit Brussel
Brussels, Belgium, 1000