Status:
UNKNOWN
The Function of PA, RBP and TRSF in Malnutrition Detecting and Nutritional Status Monitoring for NPC Patients
Lead Sponsor:
Zhao Chong
Collaborating Sponsors:
Wu Jieping Medical Foundation
Conditions:
Nasopharyngeal Carcinoma
Malnutrition
Eligibility:
All Genders
18-60 years
Brief Summary
The purpose of this study is to study the function of pre-albumin, retinol conjugated protein and transferrin in early malnutrition detecting and nutritional status dynamic monitoring for local advanc...
Eligibility Criteria
Inclusion
- Newly histologic diagnosis of nasopharyngeal carcinoma(WHO II/III)
- All genders，range from 18～60 years old
- Karnofsky performance status(KPS) ≥ 80
- Clinical stage III\~IVb(UICC 8th)
- Without significant digestive system disease，nutritional and metabolic diseases or endocrine disease
- Without significant cardiac，respiratory，kidney or liver disease
- Not received radiotherapy, chemotherapy and other anti-tumor treatment(including immunotherapy)
- white blood cell(WBC) count ≥ 4×109/L, neutrophile granulocyte(NE) count ≥ 1.5×109/L, Hemoglobin(HGB) ≥ 10g/L, platelet(PLT) count ≥ 100×109/L
- alanine aminotransferase (ALT) or aspartate aminotransferase(AST) \< 1.5×upper limit of normal(ULN), bilirubin \< 1.5×ULN, alanine aminotransferase (CCR) ≥ 30ml/min
- Inform consent form
Exclusion
- Distance metastases
- Second malignancy within 5 years
- Drug or alcohol addition
- Do not have full capacity for civil acts
- Active systemic infections
- Chronic consumptions
- Mental disorder
- Pregnancy or lactation
- Concurrent immunotherapy or hormone therapy for other diseases
- Severe complication, eg, uncontrolled hypertension
Key Trial Info
Start Date :
September 12 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03240835
Start Date
September 12 2017
End Date
December 31 2023
Last Update
January 31 2023
Active Locations (1)
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1
Cancer Center, Sun Yat-sen University
Guangzhou, Guangdong, China, 510060