Status:

RECRUITING

Changes in Sensitivity, Taste and Smell in Stroke Patients

Lead Sponsor:

University of Giessen

Conditions:

Dysphagia

Stroke

Eligibility:

All Genders

18+ years

Brief Summary

This study evaluates changes in swallowing using endoscopic swallowing studies and measuring of pharyngeal sensitivity, taste and smell in stroke patients. Younger (\<60 years) and older (\>60 years) ...

Detailed Description

Stroke is the second leading cause of death. At least 50% of stroke patients develop dysphagia, leading to aspiration pneumonia, which is the main cause of death in stroke \[2\]. It is assumed that n...

Eligibility Criteria

Inclusion

  • Volunteers:
  • informed consent
  • Stroke patients:
  • informed consent
  • new supratentorial stroke (\<72 hours old) confirmed by CT (computed tomography) or MRI (magnetic resonance imaging)

Exclusion

  • pre-existing stroke oder dysphagia
  • extensive white matter lesions in CT- or MRI-scan
  • allergies to odorous substances or flavoring
  • contraindications for FEES (flexible endoscopic evaluation of swallowing), CT or MRI (stroke patients only)

Key Trial Info

Start Date :

October 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT03240965

Start Date

October 1 2017

End Date

December 1 2026

Last Update

December 1 2023

Active Locations (1)

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1

Universitätsklinikum Gießen

Giessen, Hesse, Germany, 35392