Status:
COMPLETED
Endothelial and Microvascular Functions in Patients With Myocardial Ischemia
Lead Sponsor:
Rio de Janeiro State University
Collaborating Sponsors:
Camillo L.C. Junqueira
Esmeralci Ferreira
Conditions:
Microcirculation; Biomarkers; Myocardial Ischemia
Eligibility:
All Genders
18-65 years
Brief Summary
Cardiovascular diseases (CVD) are responsible, throughout the world, for high mortality rates and cardiovascular morbidity. Endothelial dysfunction is the earliest marker of clinical atherosclerosis d...
Detailed Description
A cross-sectional study was carried out with 50 participants: 25 with myocardial ischemia detected by scintigraphy and normal coronarography (Ischemic Patient - IP) and 25 healthy non-ischemic individ...
Eligibility Criteria
Inclusion
- The study population consisted of 50 patients of both sexes, stratified into two groups: patients with myocardial ischemia detected by scintigraphy (group IP, n = 25) and healthy individuals (CG group, n = 25). In the patients who underwent scintigraphy with tomographic sections and presented any type of image attenuation during the examination, they also underwent a complementary prone position technique. Patients without these characteristics scintigraphy methodologies were excluded from the study.
Exclusion
- Exclusion criteria were adopted: patients with type 1 or 2 Diabetes Mellitus, heart failure, myocardial infarction or brain stroke with less than three months of the event, chronic renal disease, users of hormonal or non-hormonal anti-inflammatory drugs, recent trauma (less than three months) autoimmune diseases, active infectious processes, presence of neoplasia, use of Aspirin (anti-inflammatory dose), obesity with BMI\>35 kg/m², uncontrolled hypertensive patients, resistant hypertensives, and non-compliance in the examinations or with the signature of the Consent Form.
Key Trial Info
Start Date :
March 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 30 2015
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03243968
Start Date
March 1 2014
End Date
August 30 2015
Last Update
August 9 2017
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