Status:
COMPLETED
Efficacy of HFNC Versus NIV for Prevent Reintubation in Sepsis Patients
Lead Sponsor:
Mahidol University
Conditions:
Post Extubation Respiratory Failure
Re-intubation
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Post extubation respiratory failure occur in 30% of extubated patients. More than 50% of them required reintubation. Noninvasive positive pressure ventilation (NIV) had been reported as an effective t...
Detailed Description
Post extubation respiratory failure occur in 30% of extubated patients. More than 50% of them required reintubation. Noninvasive positive pressure ventilation (NIV) had been reported as an effective t...
Eligibility Criteria
Inclusion
- Diagnosis of sepsis or septic shock according to the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
- Depended on mechanical ventilator for more than 48 hours
- Plan for extubation due to successful weaning
Exclusion
- Patient with tracheostomy
- Recent upper abdominal surgery
- Wound at face that prohibit face-mask application
- Patient or 1st degree relative not agree to participate trial
- Physician prefer either NIV or HFNC for the patient
Key Trial Info
Start Date :
May 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 31 2019
Estimated Enrollment :
222 Patients enrolled
Trial Details
Trial ID
NCT03246893
Start Date
May 1 2017
End Date
October 31 2019
Last Update
February 2 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University
Bangkok, Thailand, 10700