Status:
UNKNOWN
Population Pharmacokinetics of Antibiotics in Critically Ill Children (POPSICLE)
Lead Sponsor:
Radboud University Medical Center
Conditions:
Critical Illness
Infectious Disease
Eligibility:
All Genders
Up to 18 years
Brief Summary
Infections are common on the Intensive Care for both adult and pediatric patients. Adequately dosing antibiotic treatment is of vital importance but both under- and overdosing is frequent due to patho...
Detailed Description
Approximately one third of all critically ill children develop infectious disease related complications. Mortality due to infections can be as high as 30-45%. In up to 41% of adult critically ill pati...
Eligibility Criteria
Inclusion
- 0 to 18 years of postnatal age;
- \>37 weeks of gestational age (in children less than 6 months of postnatal age);
- Admitted to pediatric intensive care unit;
- Indwelling central line or arterial line in place for clinical purposes, or regular blood work for clinical reasons;
- Antibiotic therapy already prescribed by treating physician;
- Written informed consent (IC).
Exclusion
- Language or cognitive inability to understand written and oral informed consent.
Key Trial Info
Start Date :
May 24 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2020
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT03248349
Start Date
May 24 2017
End Date
October 1 2020
Last Update
March 13 2020
Active Locations (1)
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1
Radboudumc
Nijmegen, Gelderland, Netherlands, 6525GA