Status:

TERMINATED

Human Brain Adaptation to Chronic Pain and Its Effects on Opioid Use

Lead Sponsor:

Washington University School of Medicine

Conditions:

Pain, Chronic

Opioid Use

Eligibility:

All Genders

18-65 years

Brief Summary

The purpose of this study is to determine if the research results obtained in animal models of pain - that show that being in pain for some time increases opioid use beyond what is expected to treat t...

Detailed Description

The prevalence of chronic pain is very high in the US at approximately 30%. More than 10% of adults report having daily pain. Opioid pain medications \[such as morphine\] are prescribed for some pain ...

Eligibility Criteria

Inclusion

  • Age 18-65
  • With and without history of chronic muscle-skeletal pain \*
  • Scheduled to undergo elective abdominal surgery requiring overnight hospital admission
  • Opioid naïve\*\*
  • Willing to comply with study procedures as outlined in the protocol
  • Willing and able to provide informed consent
  • Having an email address and access to a computer or electronic tablet

Exclusion

  • Current use of opioids (includes ANY use in past 3 months)
  • Cancer diagnosis
  • Patient presenting the following documented conditions:
  • Untreated psychosis Current suicidal ideation Current substance abuse

Key Trial Info

Start Date :

August 30 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 11 2020

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT03248765

Start Date

August 30 2017

End Date

September 11 2020

Last Update

October 14 2020

Active Locations (1)

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Washington University in St Louis School of Medicine

St Louis, Missouri, United States, 63110