Status:

COMPLETED

Duloxetine and Dexamethasone for Improving Postoperative Pain

Lead Sponsor:

Ain Shams University

Conditions:

Post Operative Pain Control

Eligibility:

FEMALE

25-35 years

Phase:

PHASE4

Brief Summary

75 female patients were randomly allocated into one of three equal groups. Group I(GI) received Dulox 60 mg orally and 100 ml 0.9% sodium chloride solution (NS) intravenous infusion (IVI) over 15 min,...

Detailed Description

This study was designed to be a randomized, placebo-controlled, double-blinded parallel study and this study was carried out at Ain-Shams university hospitals, from December 2014 to January2016, on 75...

Eligibility Criteria

Inclusion

  • female patients aged between 25 and 35 years old of the American Society of Anesthesiologists (ASA) physical status I and II scheduled for elective laparoscopic gynecological surgeries (for infertility) under general anesthesia.

Exclusion

  • patient's refusal,
  • duration of surgery more than 90 minutes,
  • allergy to any drugs of the study,
  • smokers, history of drug or alcohol abuse,
  • treatment with antidepressants,
  • history of diabetes or epilepsy,
  • , history of chronic pain or daily intake of analgesics within 24 h before surgery,
  • treatment with systemic glucocorticoids within 4 weeks before surgery and (9) impaired kidney or liver functions. -

Key Trial Info

Start Date :

December 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2016

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT03250494

Start Date

December 1 2014

End Date

January 1 2016

Last Update

August 15 2017

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