Status:

COMPLETED

Effects of Low Level Laser Therapy on Functional Capacity and DNA Damage of Patients With Chronic Kidney Failure

Lead Sponsor:

Federal University of Health Science of Porto Alegre

Conditions:

Low-Level Light Therapy

Renal Insufficiency, Chronic

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

This study aims to verify the effects of low level laser therapy (LLLT) on functional capacity, DNA damage, lower limbs muscle strength, quadriceps muscle architecture, muscle pain and perception of l...

Detailed Description

Chronic kidney disease (CKD) consists of kidney damage and progressive and irreversible loss of kidney function and in its later stage (terminal phase) is called chronic kidney failure (CKF). Although...

Eligibility Criteria

Inclusion

  • Patients with chronic kidney failure on hemodialysis for more than 3 months;
  • Dialysis with weekly frequency of 3 times/week;
  • Adequate urea clearance rate during hemodialysis (Kt/V ≥ 1.2 or URR ≥65%).

Exclusion

  • Cognitive dysfunction
  • Epidermal lesions at the site of laser application
  • Patients with active carcinoma
  • Patients with recent sequel of stroke (three months)
  • Recent myocardium acute infarction (two months)
  • Uncontrolled hypertension (SBP\> 230 mmHg and DBP\> 120 mmHg)
  • Grade IV heart failure according to the New York Heart Association or decompensated
  • Unstable angina
  • Peripheral vascular changes in lower limbs such as deep venous thrombosis
  • Disabling osteoarticular or musculoskeletal disease
  • Uncontrolled diabetes (glycemia\> 300mg/dL)
  • Febrile condition and/or infectious disease
  • Active smoking.

Key Trial Info

Start Date :

September 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 31 2018

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT03250715

Start Date

September 1 2017

End Date

August 31 2018

Last Update

July 30 2020

Active Locations (1)

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Federal University of Health Sciences of Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil, 90050-170