Status:
COMPLETED
Role of the Endothelium in Stroke-like Episode Among CDG Patients
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
URC-CIC Paris Descartes Necker Cochin
Conditions:
Congenital Disorders of Glycosylation
Eligibility:
All Genders
6+ years
Phase:
NA
Brief Summary
The aim of the study is to evaluate the role of the endothelial barrier in the occurrence of stroke-like episode. And to study the protein C system on the surface of the endothelium.
Detailed Description
The study consists in isolating endothelial progenitor cells in peripheral blood. After blood puncture, PBMC (peripheral blood mononuclear cell) are isolated by Ficoll gradient and then culturing in a...
Eligibility Criteria
Inclusion
- patients with CDG molecularly diagnosed
- with stroke-like history or not
Exclusion
- rejection to participate in research
Key Trial Info
Start Date :
November 23 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 26 2019
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT03250728
Start Date
November 23 2017
End Date
April 26 2019
Last Update
September 15 2025
Active Locations (1)
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1
Hopital Necker enfants malades
Paris, Paris, France, 75015