Status:

COMPLETED

Gene Polymorphisms of Corticosteroid-induced Ocular Hypertension

Lead Sponsor:

Maastricht University Medical Center

Conditions:

Corticosteroid Induced Ocular Hypertension/Glaucoma

Eligibility:

All Genders

18+ years

Brief Summary

Glaucoma is one of the most prevalent eye diseases and the second most common cause of blindness worldwide. The most common form is primary open angle glaucoma (POAG). Glaucoma is a slowly progressing...

Eligibility Criteria

Inclusion

  • Use of corticosteroids:
  • Patients treated with Ozurdex (an intravitreal dexamethasone implant
  • Patients treated with subconjunctival Triamcinolone/ Celestone injections
  • Patients treated with corticosteroids after a corneal surgery
  • Patients treated with corticosteroids after a refractive surgery
  • Patients treated with corticosteroids after a cataract surgery
  • Patients treated with corticosteroids for macular edema
  • Patients exposed to corticosteroids for other diseases such as uveitis
  • When using topical corticosteroids, time of use \> 3 months
  • Age \> 18 year and mentally competent
  • Patient from the Maastricht University Medical Centre+ (MUMC+), the Netherlands

Exclusion

  • Age \< 18 year
  • Mentally not able to participate or give permission
  • Not able to communicate in Dutch
  • Patients with a type of uveitis that might cause a decrease of the IOP
  • When using topical corticosteroids, time of use \< 3 months.

Key Trial Info

Start Date :

September 13 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 1 2020

Estimated Enrollment :

370 Patients enrolled

Trial Details

Trial ID

NCT03250819

Start Date

September 13 2017

End Date

May 1 2020

Last Update

June 1 2020

Active Locations (1)

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University Eye Clinic Maastricht, Maastricht UMC+

Maastricht, Limburg, Netherlands, 6229 HX