Status:

RECRUITING

Uterus Transplantation From a Multi-organ Donor

Lead Sponsor:

University Hospital, Ghent

Conditions:

Infertility, Female

Mayer Rokitansky Kuster Hauser Syndrome

Eligibility:

FEMALE

18-38 years

Phase:

NA

Brief Summary

Uterus transplantation: screening, in vitro fertilization \[IVF\] treatment to be able to freeze embryos, uterus transplantation, pregnancy and afterwards removal of the uterus.

Eligibility Criteria

Inclusion

  • Female with Maier-Rokitansky-Kuster-Hauser syndrome
  • Mucosal neovagina of at least 7 cm
  • In a stable relationship for at least 1 year
  • Child wish
  • Good renal function (and presence of both kidneys)
  • Psychologically stable and compliant
  • At least 8 frozen embryos after IVF/intracytoplasmic sperm injection \[ICSI\]
  • Living in Belgium and a good health insurance
  • Willing and able to provide informed consent

Exclusion

  • Major pelvic surgery
  • Major chronic illnesses
  • Other risk factors or malignancies
  • BMI \> 30

Key Trial Info

Start Date :

November 3 2016

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2027

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT03252795

Start Date

November 3 2016

End Date

December 31 2027

Last Update

February 14 2024

Active Locations (1)

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1

Ghent University Hospital - Women's Clinic

Ghent, Belgium, 9000