Status:
COMPLETED
Study in Leptomeningeal Metastases of Breast Cancer
Lead Sponsor:
Institut du Cancer de Montpellier - Val d'Aurelle
Conditions:
Breast Cancer
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
Breast cancer (BC) is the most frequent cause of leptomeningeal metastases (LM) .As for brain parenchymal metastases, the incidence of LM seems to be increasing, due to the growing incidence of metast...
Detailed Description
Breast cancer (BC) is the most frequent cause of leptomeningeal metastases (LM). As for brain parenchymal metastases, the incidence of LM seems to be increasing, due to the growing incidence of metast...
Eligibility Criteria
Inclusion
- Male or female patient ≥ 18 years-old, no age limit;
- Histologically confirmed diagnosis of BC;
- Hormone receptors and HER2 statuses of the primary tumor available;
- Suspected LM based on clinical symptoms or signs, or radiological abnormalities;
- Indication of diagnosis lumbar puncture decided by the oncologist in charge of the patient;
- Patients must be affiliated to a Social Security System;
- Patient information and written informed consent form signed prior to any study specific procedures.
Exclusion
- History of other cancer(s) than the BC (except completely resected non-melanoma skin cancer or successfully treated in situ carcinoma).
- Hormone receptors and/or HER2 statuses of the primary tumor not available;
- Patients with a medical contra-indication to the realization of a lumbar puncture;
- Patients with psychological, family, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule;
- Patients who are pregnant or breast-feeding.
- Legal incapacity or limited legal capacity.
Key Trial Info
Start Date :
January 6 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 15 2020
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT03252912
Start Date
January 6 2017
End Date
September 15 2020
Last Update
October 19 2020
Active Locations (1)
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1
Institut régional du Cancer de Montpellier
Montpellier, France, 34298