Status:
COMPLETED
Efficacy and Safety of Melatonin and Clonazepam for IRBD
Lead Sponsor:
Kyung Hee University Hospital at Gangdong
Conditions:
REM Sleep Behavior Disorder
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
This study aimed to evaluate influence of melatonin or clonazepam treatment on symptom and polysomnographic parameters in patients with idiopathic REM sleep behavior disorder.
Detailed Description
This study is open-label parallel trial with 4 weeks treatment with slow-release melatonin (Circadin) or with clonazepam (Rivotril). Polysomnography, symptom diary and questionnaire (Clinical Global ...
Eligibility Criteria
Inclusion
- REM sleep behavior disorder (ICSD-3 criteria)
Exclusion
- Neurological disorder including epilepsy or stroke
- History of psychiatric illness
- Neurodegenerative disease including dementia or parkinsonism.
- Medication affecting sleep within 1 month
- Intake of melatonin or clonazepam within 1 week.
- Unable to complete questionnaires
Key Trial Info
Start Date :
November 9 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2020
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT03255642
Start Date
November 9 2017
End Date
December 1 2020
Last Update
February 21 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Kyung Hee University Hospital at Gangdong
Seoul, South Korea, 05269