Status:
COMPLETED
Actionable Results: Bloodstream Infection Molecular Assay Evaluation
Lead Sponsor:
Foundation for Innovative New Diagnostics, Switzerland
Conditions:
Bloodstream Infection
Eligibility:
All Genders
Phase:
NA
Brief Summary
A number of rapid panel-based molecular assays for direct organism identification and resistance characterization in positive blood culture bottles are now commercially available. They have been shown...
Detailed Description
The study will address the following questions: 1. What impact can we project if additional diagnostic information were to be provided to clinicians in terms of patient outcomes, costs, and antibioti...
Eligibility Criteria
Inclusion
- For patients of Princess Marina Hospital: all participants who have a blood culture done as part of routine clinical care that is found to be positive through routine laboratory testing from Monday-Friday 8am-3pm (excluding holidays) will be eligible for inclusion in the study, regardless of age and co-morbidities.
- For the professionals making use of molecular testing: Attending physicians (paediatricians, internists, and physician trainees \[residents, medical officers, interns\]) caring for adults and children who are enrolled in the study, Microbiologists and microbiology technologists who have experience operating the BioFire FilmArray and/or traditional blood culture incubation systems at the laboratory.
Exclusion
- For patients of Princess Marina Hospital: Individuals who have previously participated in the study by having a blood culture positive in the week prior will not be eligible to participate again within the 7-day time frame.
- For professionals making use of molecular testing: Individuals working with patients or laboratory samples at Princess Marina Hospital for less than one month will not be asked to participate.
Key Trial Info
Start Date :
May 24 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2020
Estimated Enrollment :
312 Patients enrolled
Trial Details
Trial ID
NCT03255759
Start Date
May 24 2018
End Date
March 31 2020
Last Update
March 10 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Princess Marina Hospital
Gaborone, Botswana