Status:
COMPLETED
Effects of Periodontal Treatment on HIV-infected Patients
Lead Sponsor:
University of Sao Paulo
Conditions:
HIV/AIDS
Periodontal Diseases
Eligibility:
All Genders
36+ years
Phase:
NA
Brief Summary
Periodontal diseases, such as chronic periodontitis (CP), frequently occur in immunosuppressed patients, including HIV-infected patients. The immunosuppression resulted by the HIV infection can justif...
Detailed Description
Investigators will develop one quasi-experimental study in HIV patients (N=15) and non-HIV patients (N=15) presenting CP. Candida spp count and salivary and gingival crevicular fluid concentrations of...
Eligibility Criteria
Inclusion
- General for both groups/arms: Patients with at least 15 teeth; with chronic periodontitis (at least 2 sites with pocket probing depth ≥ 5mm and clinical attachment loss \>4mm); no use of antibiotics for the 6 months previous to study enrolment.
- For HIV-infected group: CD4 T lymphocytes \< 200 cel/mm3, stable HAART for the 6 months previous to study enrollment.
Exclusion
- General for both groups/arms: periodontal treatment and use of antibiotics for the 6 months previous to study enrollment; smoking; complex systemic conditions.
Key Trial Info
Start Date :
July 2 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 8 2019
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT03262402
Start Date
July 2 2017
End Date
April 8 2019
Last Update
March 27 2020
Active Locations (1)
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1
School of Dentistry of Ribeirão Preto, University of São Paulo
Ribeirão Preto, São Paulo, Brazil, 14040-904