Status:
UNKNOWN
Gut Microbiota and Multiple Sclerosis
Lead Sponsor:
Assiut University
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
25-40 years
Brief Summary
Gut microbiota and multiple sclerosis Multiple sclerosis is a pro-inflammatory demyelinating disease of the central nervous system.
Detailed Description
Multiple sclerosis is a pro-inflammatory demyelinating disease of the central nervous system. The etiology of MS is complex and poorly understood. Both genetic and environmental factors play a role an...
Eligibility Criteria
Inclusion
- The study will included 40 cases of MS according to Diagnostic criteria of multiple sclerosis they classified into two types of Multiple sclerosis ,Relapsing-remitting MS (group 1), and Primary progressive MS, Secondary progressive MS, and Progressive relapsing MS (group 2).
- Each patient was submitted to the following:
- Expanded disability status scale score between 1 and 6 and functional system score.
- Demographic and clinical data (Age, sex, age of onset, severity of disease, clinical symptoms and signs, Types of treatment, duration of treatment, number of attacks).
Exclusion
- The general exclusion criteria included prior surgeries, any patients or controls currently taking antibiotics or probiotic supplements,or having a known history of disease with an disease such, rheumatoid arthritis,type-1-diabetes, and IBD, were also excluded from the study.Microbial DNA was extracted from fecal material of each sample.
Key Trial Info
Start Date :
January 4 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 4 2020
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03262870
Start Date
January 4 2018
End Date
January 4 2020
Last Update
August 29 2017
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